The Ohio River
The Ohio River shares many of the pollution problems of the Mississippi and the Missouri, but it has another unique problem that began in the Great Lakes. The problem is that there are too many mussels growing there. Zebra Mussels, Quagga Mussels and most recently the Flat Floater Mussel have been over-running the Ohio River. These Mussels were not originally in these water ways. Now that they are, there are not enough natural predators to control their growth. Their population is increasing very quickly. Already in the Great Lakes they are clogging drainage pipes and disrupting the natural system by pushing out the other organisms that eat the same food as the mussels. This is a difficult problem to treat. It would be hard to remove the mussels without damaging other organisms that you didn't want to.